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GLP-1 receptor agonists are often discussed as weight-loss medications. The physiology is broader than that. They affect glucose regulation, appetite signaling, gastric emptying, cardiovascular outcomes, and kidney health. That's why clinicians ...

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Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist for Obesity November 5, 2025 DOI: 10.1056/NEJMdo008238 New for the treatment of obesity - and so many additional indications being studied - orforglipron. What have

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Glucagon-like peptide-1 receptor agonists in type 2 diabetes: Evidence for disease modification and therapeutic switching

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